AOD‑9604 is a synthetic peptide derived from the C‑terminal fragment of human growth hormone (hGH, amino acids 177–191, with an added tyrosine) that is designed to selectively trigger fat metabolism without the growth-promoting or glucose‑altering effects of full‑length hGH. Preclinical studies demonstrate that AOD‑9604 significantly stimulates lipolysis and inhibits lipogenesis in obese rodent models—one study found over 50% reduction in weight gain in Zucker rats after 19 days of treatment, with no detrimental impact on insulin sensitivity. In obese mice, AOD‑9604 elevated β₃‑adrenergic receptor mRNA expression and improved fat breakdown, aiding fat mass reduction.

Peptides are available for research purposes only.
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